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Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

Skin aging is driven by intrinsic and extrinsic factors impacting on skin functionality with progressive age. One factor of this multifaceted process is cellular senescence, as it has recently been identified to contribute to a declining tissue functionality in old age. In the skin, senescent cells...

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Detalles Bibliográficos
Autores principales: Weinmüllner, Regina, Zbiral, Barbara, Becirovic, Adnan, Stelzer, Elena Maria, Nagelreiter, Fabian, Schosserer, Markus, Lämmermann, Ingo, Liendl, Lisa, Lang, Magdalena, Terlecki-Zaniewicz, Lucia, Andriotis, Orestis, Mildner, Michael, Golabi, Bahar, Waidhofer-Söllner, Petra, Schedle, Karl, Emsenhuber, Gerhard, Thurner, Philipp J., Tschachler, Erwin, Gruber, Florian, Grillari, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060247/
https://www.ncbi.nlm.nih.gov/pubmed/32194977
http://dx.doi.org/10.1038/s41514-020-0042-x