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CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling
Expression of the matricellular protein CCN1 (CYR61) is associated with inflammation and is required for successful wound repair. Here, we show that CCN1 binds bacterial pathogen-associated molecular patterns including peptidoglycans of Gram-positive bacteria and lipopolysaccharides of Gram-negative...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060279/ https://www.ncbi.nlm.nih.gov/pubmed/32144270 http://dx.doi.org/10.1038/s41467-020-15075-5 |