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Loss of Estrogen Receptors is Associated with Increased Tumor Aggression in Laryngeal Squamous Cell Carcinoma

Laryngeal squamous cell carcinoma (LSCC) responds to 17β-estradiol via estrogen-receptor (ER, transcribed from ESR1) dependent mechanisms, but is not recognized as a hormonally responsive cancer. 17β-estradiol production by LSCC cell lines UM-SCC-11A and UM-SCC-12 was examined. Wild type (WT) and ES...

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Detalles Bibliográficos
Autores principales: Verma, Anjali, Schwartz, Nofrat, Cohen, David J., Patel, Vaidehi, Nageris, Benny, Bachar, Gideon, Boyan, Barbara. D., Schwartz, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060328/
https://www.ncbi.nlm.nih.gov/pubmed/32144339
http://dx.doi.org/10.1038/s41598-020-60675-2