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Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model

In glaucoma, retinal ganglion cells are damaged, leading to the progressive constriction of the visual field. We have previously shown that the valosin-containing protein (VCP) modulators, Kyoto University Substance (KUS)121 and KUS187, prevent the death of retinal ganglion cells in animal models of...

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Detalles Bibliográficos
Autores principales: Hasegawa, Tomoko, Ikeda, Hanako Ohashi, Gotoh, Norimoto, Iida, Kei, Iwai, Sachiko, Nakano, Noriko, Kakizuka, Akira, Tsujikawa, Akitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060332/
https://www.ncbi.nlm.nih.gov/pubmed/32144342
http://dx.doi.org/10.1038/s41598-020-61160-6