mRNA Transfection-Induced Activation of Primary Human Monocytes and Macrophages: Dependence on Carrier System and Nucleotide Modification

Monocytes and macrophages are key players in maintaining immune homeostasis. Identifying strategies to manipulate their functions via gene delivery is thus of great interest for immunological research and biomedical applications. We set out to establish conditions for mRNA transfection in hard-to-tr...

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Detalles Bibliográficos
Autores principales: Moradian, Hanieh, Roch, Toralf, Lendlein, Andreas, Gossen, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060354/
https://www.ncbi.nlm.nih.gov/pubmed/32144280
http://dx.doi.org/10.1038/s41598-020-60506-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060354/
https://www.ncbi.nlm.nih.gov/pubmed/32144280
http://dx.doi.org/10.1038/s41598-020-60506-4

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