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3D structure of the transporter ABCG2—What's new?

ABCG2 belongs to the ABC transporter superfamily and functions as a poly‐specific efflux pump. As it can transport a broad spectrum of substrates out of cells, ABCG2 is thought to alter the pharmacokinetics of drugs applied to treat certain diseases. Especially, its potential to induce resistance to...

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Detalles Bibliográficos
Autores principales: Eckenstaler, Robert, Benndorf, Ralf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060357/
https://www.ncbi.nlm.nih.gov/pubmed/31985041
http://dx.doi.org/10.1111/bph.14991