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High Glucose Induces Endothelial COX2 and iNOS Expression via Inhibition of Monomethyltransferase SETD8 Expression

Cyclooxygenase 2 (COX2) and inducible nitric oxide synthase (iNOS) overexpression results in endothelial apoptosis, thus mediating vascular endothelial injury in hyperglycaemia. E26 transformation-specific sequence transcription factor-1 (ESE-1), which belongs to the E26 transformation-specific fami...

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Detalles Bibliográficos
Autores principales: Qi, Jie, Wu, Qichao, Cheng, Qian, Chen, Xiangyuan, Zhu, Minmin, Miao, Changhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060408/
https://www.ncbi.nlm.nih.gov/pubmed/32185234
http://dx.doi.org/10.1155/2020/2308520