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Efficient recruitment of c‐FLIP(L) to the death‐inducing signaling complex leads to Fas resistance in natural killer‐cell lymphoma

Activation‐induced cell death (AICD) mediated by the Fas/Fas ligand (FasL) system plays a key role in regulating immune response. Although normal natural killer (NK) cells use this system for their homeostasis, malignant NK cells seem to disrupt the process. Extranodal NK/T‐cell lymphoma, nasal type...

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Detalles Bibliográficos
Autores principales: Masuda, Azuchi, Isobe, Yasushi, Sugimoto, Koichi, Yoshimori, Mayumi, Arai, Ayako, Komatsu, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060462/
https://www.ncbi.nlm.nih.gov/pubmed/31908105
http://dx.doi.org/10.1111/cas.14296