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ALDH1A3‐mTOR axis as a therapeutic target for anticancer drug‐tolerant persister cells in gastric cancer

Tumors consist of heterogeneous cell populations that contain cancer cell subpopulations with anticancer drug‐resistant properties called “persister” cells. While this early‐phase drug tolerance is known to be related to the stem cell‐like characteristic of persister cells, how the stem cell‐related...

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Detalles Bibliográficos
Autores principales: Kawakami, Ryuhei, Mashima, Tetsuo, Kawata, Naomi, Kumagai, Koshi, Migita, Toshiro, Sano, Takeshi, Mizunuma, Nobuyuki, Yamaguchi, Kensei, Seimiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060474/
https://www.ncbi.nlm.nih.gov/pubmed/31960523
http://dx.doi.org/10.1111/cas.14316