Modulating NMDA receptors to treat MK-801-induced schizophrenic cognition deficit: effects of clozapine combining with PQQ treatment and possible mechanisms of action

BACKGROUND: Clozapine has remarkable efficacy on both negative and cognitive symptoms of schizophrenia due to its slight activation of NMDA receptor. In fact, much evidence to the contrary. NMDAR is a complex containing specific binding sites, which are regulated to improve negative symptoms and cog...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Xingqin, Cai, Gangming, Mao, Shishi, Xu, Dong, Xu, Xijie, Zhang, Rongjun, Yao, Zhiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060539/
https://www.ncbi.nlm.nih.gov/pubmed/32143671
http://dx.doi.org/10.1186/s12888-020-02509-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060539/
https://www.ncbi.nlm.nih.gov/pubmed/32143671
http://dx.doi.org/10.1186/s12888-020-02509-z

Ejemplares similares