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Modulating NMDA receptors to treat MK-801-induced schizophrenic cognition deficit: effects of clozapine combining with PQQ treatment and possible mechanisms of action

BACKGROUND: Clozapine has remarkable efficacy on both negative and cognitive symptoms of schizophrenia due to its slight activation of NMDA receptor. In fact, much evidence to the contrary. NMDAR is a complex containing specific binding sites, which are regulated to improve negative symptoms and cog...

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Detalles Bibliográficos
Autores principales:	Zhou, Xingqin, Cai, Gangming, Mao, Shishi, Xu, Dong, Xu, Xijie, Zhang, Rongjun, Yao, Zhiwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060539/ https://www.ncbi.nlm.nih.gov/pubmed/32143671 http://dx.doi.org/10.1186/s12888-020-02509-z

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