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Genome-wide analysis of constitutional DNA methylation in familial melanoma

BACKGROUND: Heritable epigenetic alterations have been proposed as an explanation for familial clustering of melanoma. Here we performed genome-wide DNA methylation analysis on affected family members not carrying pathogenic variants in established melanoma susceptibility genes, compared with health...

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Detalles Bibliográficos
Autores principales: Salgado, Catarina, Gruis, Nelleke, Heijmans, Bastiaan T., Oosting, Jan, van Doorn, Remco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060565/
https://www.ncbi.nlm.nih.gov/pubmed/32143689
http://dx.doi.org/10.1186/s13148-020-00831-7