Targeting human epidermal growth factor receptor 2 enhances radiosensitivity and reduces the metastatic potential of Lewis lung carcinoma cells

BACKGROUND: Sublethal radiation induces matrix metalloproteinase 9 (MMP-9)-mediated radioresistance in Lewis lung carcinoma (LLC) cells and their metastatic dissemination. We aim to determine if EGFR/HER2 activation associates with MMP-9-mediated radioresistance and invasiveness in irradiated LLC ce...

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Detalles Bibliográficos
Autores principales: Tien, Yun, Tsai, Chiao-Ling, Hou, Wei-Hsien, Chiang, Yun, Hsu, Feng-Ming, Tsai, Yu-Chieh, Cheng, Jason Chia-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060577/
https://www.ncbi.nlm.nih.gov/pubmed/32143669
http://dx.doi.org/10.1186/s13014-020-01493-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060577/
https://www.ncbi.nlm.nih.gov/pubmed/32143669
http://dx.doi.org/10.1186/s13014-020-01493-8

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