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Targeting human epidermal growth factor receptor 2 enhances radiosensitivity and reduces the metastatic potential of Lewis lung carcinoma cells

BACKGROUND: Sublethal radiation induces matrix metalloproteinase 9 (MMP-9)-mediated radioresistance in Lewis lung carcinoma (LLC) cells and their metastatic dissemination. We aim to determine if EGFR/HER2 activation associates with MMP-9-mediated radioresistance and invasiveness in irradiated LLC ce...

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Detalles Bibliográficos
Autores principales:	Tien, Yun, Tsai, Chiao-Ling, Hou, Wei-Hsien, Chiang, Yun, Hsu, Feng-Ming, Tsai, Yu-Chieh, Cheng, Jason Chia-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060577/ https://www.ncbi.nlm.nih.gov/pubmed/32143669 http://dx.doi.org/10.1186/s13014-020-01493-8

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