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Is the HERV-K HML-2 Xq21.33, an endogenous retrovirus mutated by gene conversion of chromosome X in a subset of African populations, associated with human breast cancer?

The human endogenous retroviruses HERV-K HML-2 have been considered a possible cause of human breast cancer (BrC). A HERV-K HML-2 fully intact provirus Xq21.33 was recently identified in some West African people. We used PCR technology to search for the Xq21.33 provirus in DNA from Nigerian women wi...

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Detalles Bibliográficos
Autores principales: Kaplan, Mark H., Contreras-Galindo, Rafael, Jiagge, Evelyn, Merajver, Sofia D., Newman, Lisa, Bigman, Galya, Dosik, Michael H., Palapattu, Ganesh S., Siddiqui, Javed, Chinnaiyan, Arul M., Adebamowo, Sally, Adebamowo, Clement
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060579/
https://www.ncbi.nlm.nih.gov/pubmed/32165916
http://dx.doi.org/10.1186/s13027-020-00284-w