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Characterization of HIV-1 uncoating in human microglial cell lines

BACKGROUND: After viral fusion with the cell membrane, the conical capsid of HIV-1 disassembles by a process called uncoating. Previously we have utilized the CsA washout assay, in which TRIM-CypA mediated restriction of viral replication is used to detect the state of the viral capsid, to study the...

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Detalles Bibliográficos
Autores principales: Ingram, Zachary, Taylor, Melanie, Okland, Glister, Martin, Richard, Hulme, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060623/
https://www.ncbi.nlm.nih.gov/pubmed/32143686
http://dx.doi.org/10.1186/s12985-020-01301-5