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Different transcriptome profiles between human retinoblastoma Y79 cells and an etoposide-resistant subline reveal a chemoresistance mechanism

BACKGROUND: Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms to reveal transcriptome profiles and identify any different...

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Detalles Bibliográficos
Autores principales: Song, Wen-ping, Zheng, Si, Yao, Hong-juan, Zhou, Xiao-fei, Li, Rui, Zhang, Cheng-yue, Zhao, Jun-yang, Wang, Lie-wei, Shao, Rong-guang, Li, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060629/
https://www.ncbi.nlm.nih.gov/pubmed/32143590
http://dx.doi.org/10.1186/s12886-020-01348-6