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Analytical distributions for detailed models of stochastic gene expression in eukaryotic cells
The stochasticity of gene expression presents significant challenges to the modeling of genetic networks. A two-state model describing promoter switching, transcription, and messenger RNA (mRNA) decay is the standard model of stochastic mRNA dynamics in eukaryotic cells. Here, we extend this model t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060679/ https://www.ncbi.nlm.nih.gov/pubmed/32071224 http://dx.doi.org/10.1073/pnas.1910888117 |