Dexmedetomidine Pharmacokinetics in Neonates with Hypoxic-Ischemic Encephalopathy Receiving Hypothermia

Dexmedetomidine is a promising sedative and analgesic for newborns with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). Pharmacokinetics and safety of dexmedetomidine were evaluated in a phase I, single-center, open-label study to inform future trial strategies. We rec...

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Detalles Bibliográficos
Autores principales: McAdams, Ryan M., Pak, Daniel, Lalovic, Bojan, Phillips, Brian, Shen, Danny D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060842/
https://www.ncbi.nlm.nih.gov/pubmed/32158472
http://dx.doi.org/10.1155/2020/2582965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060842/
https://www.ncbi.nlm.nih.gov/pubmed/32158472
http://dx.doi.org/10.1155/2020/2582965

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