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From Xanthine Oxidase Inhibition to In Vivo Hypouricemic Effect: An Integrated Overview of In Vitro and In Vivo Studies with Focus on Natural Molecules and Analogues

Hyperuricemia is characterized by elevated uric acid (UA) levels on blood, which can lead to gout, a common pathology. These high UA levels are associated with increased purine ingestion and metabolization and/or its decreased excretion. In this field, xanthine oxidase (XO), by converting hypoxanthi...

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Detalles Bibliográficos
Autores principales: Serrano, João L., Figueiredo, Joana, Almeida, Paulo, Silvestre, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060854/
https://www.ncbi.nlm.nih.gov/pubmed/32184901
http://dx.doi.org/10.1155/2020/9531725