A Single Prior Injection of Methamphetamine Enhances Methamphetamine Self-Administration (SA) and Blocks SA-Induced Changes in DNA Methylation and mRNA Expression of Potassium Channels in the Rat Nucleus Accumbens

The transition from occasional to escalated psychostimulant use is accelerated by prior drug exposure. These behavioral observations may be related to long-lasting transcriptional and/or epigenetic changes induced by the drug pre-exposure. Herein, we investigated if a single methamphetamine (METH) i...

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Detalles Bibliográficos
Autores principales: Jayanthi, Subramaniam, Torres, Oscar V., Ladenheim, Bruce, Cadet, Jean Lud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060962/
https://www.ncbi.nlm.nih.gov/pubmed/31758400
http://dx.doi.org/10.1007/s12035-019-01830-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060962/
https://www.ncbi.nlm.nih.gov/pubmed/31758400
http://dx.doi.org/10.1007/s12035-019-01830-3

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