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Alterations of Transcription of Genes Coding Anti-oxidative and Mitochondria-Related Proteins in Amyloid β Toxicity: Relevance to Alzheimer’s Disease

A growing body of evidence indicates that pathological forms of amyloid beta (Aβ) peptide contribute to neuronal degeneration and synaptic loss in Alzheimer’s disease (AD). In this study, we investigated the impact of exogenous Aβ(1-42) oligomers (AβO) and endogenously liberated Aβ peptides on trans...

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Detalles Bibliográficos
Autores principales: Cieślik, Magdalena, Czapski, Grzegorz A., Wójtowicz, Sylwia, Wieczorek, Iga, Wencel, Przemysław L., Strosznajder, Robert P., Jaber, Vivian, Lukiw, Walter J., Strosznajder, Joanna B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061023/
https://www.ncbi.nlm.nih.gov/pubmed/31734880
http://dx.doi.org/10.1007/s12035-019-01819-y