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Impact of BAFF Blockade on Inflammation, Germinal Center Reaction and Effector B-Cells During Acute SIV Infection

Memory B-cell dysfunctions and inefficient antibody response suggest germinal center (GC) impairments during HIV/SIV infection with possible contribution of overproduced B-cell activating factor (BAFF). To address this question, we compared proportions and functions of various B-cell subsets and fol...

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Detalles Bibliográficos
Autores principales: Borhis, Gwenoline, Trovato, Maria, Ibrahim, Hany M., Isnard, Stephane, Le Grand, Roger, Bosquet, Nathalie, Richard, Yolande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061218/
https://www.ncbi.nlm.nih.gov/pubmed/32194549
http://dx.doi.org/10.3389/fimmu.2020.00252