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Adaptive Evolution Targets a piRNA Precursor Transcription Network

In Drosophila, transposon-silencing piRNAs are derived from heterochromatic clusters and a subset of euchromatic transposon insertions, which are bound by the Rhino-Deadlock-Cutoff complex. The HP1 homolog Rhino binds to Deadlock, which recruits TRF2 to promote non-canonical transcription from both...

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Detalles Bibliográficos
Autores principales: Parhad, Swapnil S., Yu, Tianxiong, Zhang, Gen, Rice, Nicholas P., Weng, Zhiping, Theurkauf, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061269/
https://www.ncbi.nlm.nih.gov/pubmed/32101744
http://dx.doi.org/10.1016/j.celrep.2020.01.109