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Adaptive Evolution Targets a piRNA Precursor Transcription Network
In Drosophila, transposon-silencing piRNAs are derived from heterochromatic clusters and a subset of euchromatic transposon insertions, which are bound by the Rhino-Deadlock-Cutoff complex. The HP1 homolog Rhino binds to Deadlock, which recruits TRF2 to promote non-canonical transcription from both...
Autores principales: | Parhad, Swapnil S., Yu, Tianxiong, Zhang, Gen, Rice, Nicholas P., Weng, Zhiping, Theurkauf, William E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061269/ https://www.ncbi.nlm.nih.gov/pubmed/32101744 http://dx.doi.org/10.1016/j.celrep.2020.01.109 |
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