Apoptosis-related gene expression can predict the response of ovarian cancer cell lines to treatment with recombinant human TRAIL alone or combined with cisplatin

OBJECTIVES: The objectives of this study were to determine the sensitivity of ovarian cancer (OC) cell lines (TOV-21G and SKOV-3) to cisplatin and to the recombinant human TRAIL (rhTRAIL), and to evaluate the expression profile of TNFRSF10B, TNFRSF10C, TP53TG5, MDM2, BAX, BCL-2 and CASPASE-8 genes a...

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Detalles Bibliográficos
Autores principales: Braga, Letícia da Conceição, Gonçales, Nikole Gontijo, Furtado, Rafaela de Souza, de Andrade, Warne Pedro, Silva, Luciana Maria, da Silva Filho, Agnaldo Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Medicina / USP 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061320/
https://www.ncbi.nlm.nih.gov/pubmed/32187278
http://dx.doi.org/10.6061/clinics/2020/e1492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061320/
https://www.ncbi.nlm.nih.gov/pubmed/32187278
http://dx.doi.org/10.6061/clinics/2020/e1492

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