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A Study of Antidepressant Effect and Mechanism on Intranasal Delivery of BDNF-HA2TAT/AAV to Rats with Post-Stroke Depression

AIM: Post-stroke depression (PSD) is one of the most frequent neuropsychiatric disorders associated with stroke characterized by depression. The neuroplasticity hypothesis postulates that loss of brain-derived neurotrophic factor (BDNF) plays a major role in pathophysiology of PSD, and restoration o...

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Detalles Bibliográficos
Autores principales: Chen, Ce, Dong, Yingying, Liu, Fei, Gao, Chengge, Ji, Cui, Dang, Yonghui, Ma, Xiancang, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061423/
https://www.ncbi.nlm.nih.gov/pubmed/32184603
http://dx.doi.org/10.2147/NDT.S227598