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Solid-phase combinatorial synthesis using microarrays of microcompartments with light-induced on-chip cell screening

The process of drug discovery includes individual synthesis and characterization of drug candidates, followed by a biological screening, which is separated from synthesis in space and time. This approach suffers from low throughput and associated high costs, which in turn lead to inefficiency in the...

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Detalles Bibliográficos
Autores principales: Rosenfeld, A., Brehm, M., Welle, A., Trouillet, V., Heissler, S., Benz, M., Levkin, P.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061619/
https://www.ncbi.nlm.nih.gov/pubmed/32159150
http://dx.doi.org/10.1016/j.mtbio.2019.100022