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Solid-phase combinatorial synthesis using microarrays of microcompartments with light-induced on-chip cell screening
The process of drug discovery includes individual synthesis and characterization of drug candidates, followed by a biological screening, which is separated from synthesis in space and time. This approach suffers from low throughput and associated high costs, which in turn lead to inefficiency in the...
Autores principales: | Rosenfeld, A., Brehm, M., Welle, A., Trouillet, V., Heissler, S., Benz, M., Levkin, P.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061619/ https://www.ncbi.nlm.nih.gov/pubmed/32159150 http://dx.doi.org/10.1016/j.mtbio.2019.100022 |
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