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Microfluidic nutrient gradient–based three-dimensional chondrocyte culture-on-a-chip as an in vitro equine arthritis model

In this work, we describe a microfluidic three-dimensional (3D) chondrocyte culture mimicking in vivo articular chondrocyte morphology, cell distribution, metabolism, and gene expression. This has been accomplished by establishing a physiologic nutrient diffusion gradient across the simulated matrix...

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Detalles Bibliográficos
Autores principales: Rosser, J., Bachmann, B., Jordan, C., Ribitsch, I., Haltmayer, E., Gueltekin, S., Junttila, S., Galik, B., Gyenesei, A., Haddadi, B., Harasek, M., Egerbacher, M., Ertl, P., Jenner, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061638/
https://www.ncbi.nlm.nih.gov/pubmed/32159153
http://dx.doi.org/10.1016/j.mtbio.2019.100023