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Head-to-head comparison of in-house produced CD19 CAR-T cell in ALL and NHL patients

BACKGROUND: CD19 chimeric antigen receptor T (CAR-T) cells demonstrate remarkable remission rates in pediatric and adult patients with refractory or relapsed (r/r) acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL). In 2016, we initiated a clinical trial with in-house produced...

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Detalles Bibliográficos
Autores principales: Itzhaki, Orit, Jacoby, Elad, Nissani, Abraham, Levi, Michal, Nagler, Arnon, Kubi, Adva, Brezinger, Karin, Brayer, Hadar, Zeltzer, Li-at, Rozenbaum, Meir, Vernitsky, Helly, Markel, Gal, Toren, Amos, Avigdor, Abraham, Schachter, Jacob, Besser, Michal J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061891/
https://www.ncbi.nlm.nih.gov/pubmed/32152221
http://dx.doi.org/10.1136/jitc-2019-000148