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Discrete analysis of camelid variable domains: sequences, structures, and in-silico structure prediction

Antigen binding by antibodies requires precise orientation of the complementarity- determining region (CDR) loops in the variable domain to establish the correct contact surface. Members of the family Camelidae have a modified form of immunoglobulin gamma (IgG) with only heavy chains, called Heavy C...

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Detalles Bibliográficos
Autores principales: Melarkode Vattekatte, Akhila, Shinada, Nicolas Ken, Narwani, Tarun J., Noël, Floriane, Bertrand, Olivier, Meyniel, Jean-Philippe, Malpertuy, Alain, Gelly, Jean-Christophe, Cadet, Frédéric, de Brevern, Alexandre G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061911/
https://www.ncbi.nlm.nih.gov/pubmed/32185102
http://dx.doi.org/10.7717/peerj.8408