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Discrete analysis of camelid variable domains: sequences, structures, and in-silico structure prediction
Antigen binding by antibodies requires precise orientation of the complementarity- determining region (CDR) loops in the variable domain to establish the correct contact surface. Members of the family Camelidae have a modified form of immunoglobulin gamma (IgG) with only heavy chains, called Heavy C...
Autores principales: | Melarkode Vattekatte, Akhila, Shinada, Nicolas Ken, Narwani, Tarun J., Noël, Floriane, Bertrand, Olivier, Meyniel, Jean-Philippe, Malpertuy, Alain, Gelly, Jean-Christophe, Cadet, Frédéric, de Brevern, Alexandre G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061911/ https://www.ncbi.nlm.nih.gov/pubmed/32185102 http://dx.doi.org/10.7717/peerj.8408 |
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