KAP1 targets actively transcribed genomic loci to exert pleomorphic effects on RNA polymerase II activity

KAP1 (KRAB-associated protein 1) is best known as a co-repressor responsible for inducing heterochromatin formation, notably at transposable elements. However, it has also been observed to bind the transcription start site of actively expressed genes. To address this paradox, we characterized the pr...

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Detalles Bibliográficos
Autores principales: Kauzlaric, Annamaria, Jang, Suk Min, Morchikh, Mehdi, Cassano, Marco, Planet, Evarist, Benkirane, Monsef, Trono, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061982/
https://www.ncbi.nlm.nih.gov/pubmed/32068487
http://dx.doi.org/10.1098/rstb.2019.0334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061982/
https://www.ncbi.nlm.nih.gov/pubmed/32068487
http://dx.doi.org/10.1098/rstb.2019.0334

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