The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity

Forkhead box N1 (FOXN1) is a member of the forkhead box family of transcription factors and plays an important role in thymic epithelial cell differentiation and development. FOXN1 mutations in humans and mice give rise to the “nude” phenotype, which is marked by athymia. FOXN1 belongs to a subset o...

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Detalles Bibliográficos
Autores principales: Newman, Joseph A., Aitkenhead, Hazel, Gavard, Angeline E., Rota, Ioanna A., Handel, Adam E., Hollander, Georg A., Gileadi, Opher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Gene Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062188/
https://www.ncbi.nlm.nih.gov/pubmed/31914405
http://dx.doi.org/10.1074/jbc.RA119.010365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062188/
https://www.ncbi.nlm.nih.gov/pubmed/31914405
http://dx.doi.org/10.1074/jbc.RA119.010365

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