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Emerging Approaches for Regulation and Control of CAR T Cells: A Mini Review

Chimeric antigen receptor (CAR) T cells have emerged as a promising treatment for patients with advanced B-cell cancers. However, widespread application of the therapy is currently limited by potentially life-threatening toxicities due to a lack of control of the highly potent transfused cells. Rese...

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Detalles Bibliográficos
Autores principales: Brandt, Lærke J. B., Barnkob, Mike B., Michaels, Yale S., Heiselberg, Julia, Barington, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062233/
https://www.ncbi.nlm.nih.gov/pubmed/32194561
http://dx.doi.org/10.3389/fimmu.2020.00326