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Sorafenib-Loaded Nanoparticles Based on Biodegradable Dendritic Polymers for Enhanced Therapy of Hepatocellular Carcinoma

PURPOSE: In spite of its enhanced efficacy and reduced side effects in clinical hepatocellular carcinoma (HCC) therapy, the therapeutic efficacy of antitumor angiogenesis inhibitor sorafenib (SFB) is still restricted due to short in vivo half-life and drug resistance. Here, a novel SFB-loaded dendri...

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Detalles Bibliográficos
Autores principales: Li, Zihuang, Ye, Ling, Liu, Jingwen, Lian, Daizheng, Li, Xianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062400/
https://www.ncbi.nlm.nih.gov/pubmed/32184599
http://dx.doi.org/10.2147/IJN.S237335