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Tolerogenic vaccine composited with islet-derived multipeptides and cyclosporin A induces pTreg and prevents Type 1 diabetes in murine model

Regulatory T cells (Tregs) play a crucial role in the control of the initiation and progression of type 1 diabetes (T1D). Various immunological interventions including those to ex vivo expansion Tregs transfer, in vivo induction of peripherally derived Treg (pTreg) have been considered as promising...

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Detalles Bibliográficos
Autores principales: Zhou, Xian, Zhang, Shijie, Yu, Fan, Zhao, Gan, Geng, Shuang, Yu, Wencong, Wang, Xuan-Yi, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062422/
https://www.ncbi.nlm.nih.gov/pubmed/31070990
http://dx.doi.org/10.1080/21645515.2019.1616504