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Tolerogenic vaccine composited with islet-derived multipeptides and cyclosporin A induces pTreg and prevents Type 1 diabetes in murine model
Regulatory T cells (Tregs) play a crucial role in the control of the initiation and progression of type 1 diabetes (T1D). Various immunological interventions including those to ex vivo expansion Tregs transfer, in vivo induction of peripherally derived Treg (pTreg) have been considered as promising...
Autores principales: | Zhou, Xian, Zhang, Shijie, Yu, Fan, Zhao, Gan, Geng, Shuang, Yu, Wencong, Wang, Xuan-Yi, Wang, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062422/ https://www.ncbi.nlm.nih.gov/pubmed/31070990 http://dx.doi.org/10.1080/21645515.2019.1616504 |
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