Designing a therapeutic hepatitis B vaccine to circumvent immune tolerance

An effective prophylactic hepatitis B virus (HBV) vaccine has long been available but is ineffective for chronic infection. The primary cause of chronic hepatitis B (CHB) and greatest impediment for a therapeutic vaccine is the direct and indirect effects of immune tolerance to HBV antigens. The res...

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Detalles Bibliográficos
Autores principales: Whitacre, DC, Peters, CJ, Sureau, C, Nio, K, Li, F, Su, L, Jones, JE, Isogawa, M, Sallberg, M, Frelin, L, Peterson, DL, Milich, DR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062423/
https://www.ncbi.nlm.nih.gov/pubmed/31809638
http://dx.doi.org/10.1080/21645515.2019.1689745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062423/
https://www.ncbi.nlm.nih.gov/pubmed/31809638
http://dx.doi.org/10.1080/21645515.2019.1689745

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