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Revisiting the role of Dcc in visual system development with a novel eye clearing method

The Deleted in Colorectal Carcinoma (Dcc) receptor plays a critical role in optic nerve development. Whilst Dcc is expressed postnatally in the eye, its function remains unknown as Dcc knockouts die at birth. To circumvent this drawback, we generated an eye-specific Dcc mutant. To study the organiza...

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Detalles Bibliográficos
Autores principales: Vigouroux, Robin J, Cesar, Quénol, Chédotal, Alain, Nguyen-Ba-Charvet, Kim Tuyen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062470/
https://www.ncbi.nlm.nih.gov/pubmed/32096760
http://dx.doi.org/10.7554/eLife.51275