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Polyunsaturated fatty acids produce a range of activators for heterogeneous I(Ks) channel dysfunction

Repolarization and termination of the ventricular cardiac action potential is highly dependent on the activation of the slow delayed-rectifier potassium I(Ks) channel. Disruption of the I(Ks) current leads to the most common form of congenital long QT syndrome (LQTS), a disease that predisposes pati...

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Detalles Bibliográficos
Autores principales: Bohannon, Briana M., Wu, Xiaoan, Wu, Xiongyu, Perez, Marta E., Liin, Sara I., Larsson, H. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062506/
https://www.ncbi.nlm.nih.gov/pubmed/31865382
http://dx.doi.org/10.1085/jgp.201912396