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Polyunsaturated fatty acids produce a range of activators for heterogeneous I(Ks) channel dysfunction
Repolarization and termination of the ventricular cardiac action potential is highly dependent on the activation of the slow delayed-rectifier potassium I(Ks) channel. Disruption of the I(Ks) current leads to the most common form of congenital long QT syndrome (LQTS), a disease that predisposes pati...
Autores principales: | Bohannon, Briana M., Wu, Xiaoan, Wu, Xiongyu, Perez, Marta E., Liin, Sara I., Larsson, H. Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062506/ https://www.ncbi.nlm.nih.gov/pubmed/31865382 http://dx.doi.org/10.1085/jgp.201912396 |
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Correction: Polyunsaturated fatty acid analogues differentially affect cardiac Na(V), Ca(V), and K(V) channels through unique mechanisms
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