The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses

The ability of Toxoplasma gondii to inject the rhoptry kinase ROP16 into host cells results in the activation of the transcription factors STAT3 and STAT6, but it is unclear how these events impact infection. Here, parasites that inject Cre-recombinase with rhoptry proteins were used to distinguish...

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Detalles Bibliográficos
Autores principales: Chen, Longfei, Christian, David A., Kochanowsky, Joshua A., Phan, Anthony T., Clark, Joseph T., Wang, Shuai, Berry, Corbett, Oh, Jung, Chen, Xiaoguang, Roos, David S., Beiting, Daniel P., Koshy, Anita A., Hunter, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062521/
https://www.ncbi.nlm.nih.gov/pubmed/31961916
http://dx.doi.org/10.1084/jem.20181757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062521/
https://www.ncbi.nlm.nih.gov/pubmed/31961916
http://dx.doi.org/10.1084/jem.20181757

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