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Transforming growth factor–β in tissue fibrosis
TGF-β is extensively implicated in the pathogenesis of fibrosis. In fibrotic lesions, spatially restricted generation of bioactive TGF-β from latent stores requires the cooperation of proteases, integrins, and specialized extracellular matrix molecules. Although fibroblasts are major targets of TGF-...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062524/ https://www.ncbi.nlm.nih.gov/pubmed/32997468 http://dx.doi.org/10.1084/jem.20190103 |