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Re-evaluation of human BDCA-2(+) DC during acute sterile skin inflammation

Plasmacytoid dendritic cells (pDCs) produce type I interferon (IFN-I) and are traditionally defined as being BDCA-2(+)CD123(+). pDCs are not readily detectable in healthy human skin, but have been suggested to accumulate in wounds. Here, we describe a CD1a-bearing BDCA-2(+)CD123(int) DC subset that...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Ling, Gomes, Tomas, Hardman, Clare S., Vieira Braga, Felipe A., Gutowska-Owsiak, Danuta, Salimi, Maryam, Gray, Nicki, Duncan, David A., Reynolds, Gary, Johnson, David, Salio, Mariolina, Cerundolo, Vincenzo, Barlow, Jillian L., McKenzie, Andrew N.J., Teichmann, Sarah A., Haniffa, Muzlifah, Ogg, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062525/
https://www.ncbi.nlm.nih.gov/pubmed/31845972
http://dx.doi.org/10.1084/jem.20190811