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Single-cell analysis of RORα tracer mouse lung reveals ILC progenitors and effector ILC2 subsets
Lung group 2 innate lymphoid cells (ILC2s) drive allergic inflammation and promote tissue repair. ILC2 development is dependent on the transcription factor retinoic acid receptor–related orphan receptor (RORα), which is also expressed in common ILC progenitors. To elucidate the developmental pathway...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062532/ https://www.ncbi.nlm.nih.gov/pubmed/31816636 http://dx.doi.org/10.1084/jem.20182293 |