Single-cell analysis of RORα tracer mouse lung reveals ILC progenitors and effector ILC2 subsets

Lung group 2 innate lymphoid cells (ILC2s) drive allergic inflammation and promote tissue repair. ILC2 development is dependent on the transcription factor retinoic acid receptor–related orphan receptor (RORα), which is also expressed in common ILC progenitors. To elucidate the developmental pathway...

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Detalles Bibliográficos
Autores principales: Ghaedi, Maryam, Shen, Zi Yi, Orangi, Mona, Martinez-Gonzalez, Itziar, Wei, Lisa, Lu, Xiaoxiao, Das, Arundhoti, Heravi-Moussavi, Alireza, Marra, Marco A., Bhandoola, Avinash, Takei, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062532/
https://www.ncbi.nlm.nih.gov/pubmed/31816636
http://dx.doi.org/10.1084/jem.20182293

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