Syk degradation restrains plasma cell formation and promotes zonal transitions in germinal centers

Germinal centers (GCs) are sites at which B cells proliferate and mutate their antibody-encoding genes in the dark zone (DZ), followed by affinity-based selection in the light zone (LZ). B cell antigen receptor (BCR) signals induce Syk activation followed by rapid phosphatase-mediated desensitizatio...

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Detalles Bibliográficos
Autores principales: Davidzohn, Natalia, Biram, Adi, Stoler-Barak, Liat, Grenov, Amalie, Dassa, Bareket, Shulman, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062533/
https://www.ncbi.nlm.nih.gov/pubmed/31873727
http://dx.doi.org/10.1084/jem.20191043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062533/
https://www.ncbi.nlm.nih.gov/pubmed/31873727
http://dx.doi.org/10.1084/jem.20191043

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