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Edgetic perturbation signatures represent known and novel cancer biomarkers

Isoform switching is a recently characterized hallmark of cancer, and often translates to the loss or gain of domains mediating protein interactions and thus, the re-wiring of the interactome. Recent computational tools leverage domain-domain interaction data to resolve the condition-specific intera...

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Detalles Bibliográficos
Autores principales: Kataka, Evans, Zaucha, Jan, Frishman, Goar, Ruepp, Andreas, Frishman, Dmitrij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062722/
https://www.ncbi.nlm.nih.gov/pubmed/32152446
http://dx.doi.org/10.1038/s41598-020-61422-3